The clinical presentation of Von Meyenburg complexes

Hippokratia 2011; 15(2):170-173

E. Sinakos, L. Papalavrentios, D. Chourmouzi, D. Dimopoulou, A. Drevelegas, E. Akriviadis


Von Meyenburg Complexes (VMCs) is a rare clinicopathologic entity, consisting of small (<1.5cm), usually multiple and nodular cystic lesions. VMCs typically cause no symptoms or disturbances in liver function and thus in most instances they are diagnosed incidentally. We present four VMCs cases, each with a distinct clinical presentation. In two of our cases, VMCs caused mild, non-specific abdominal symptoms, including diffuse abdominal pain and discomfort. In the other two cases, in a 60-year-old woman and a 25-year-old man, the clinical presentation was implicative of an infectious hepatic process reminiscent of cholangitis and liver abscesses respectively. In each case the diagnosis was based on magnetic resonance imaging and magnetic resonance cholangiopancreatography findings showing multiple hyper-intense cystic nodules not communicating with the biliary tree. Physicians should be aware of the entire clinical spectrum of VMCs and its unique radiologic features in order to differentiate VMCs from other cystic liver lesions.