Hashimoto’s thyroiditis with rare histologic findings

Hippokratia 2002, 6(1):11 – 15

J Venizelos, M Kita, M Joiti, A Anastasilakis, D Sioutopoulou, M Leontsini, A Avramidis


Autoimmune thyroid disease consists of a spectrum of clinical and histological entities with diffuse toxic goiter at one end and Hashimoto’s thyroiditis (HT) at the other. The histologic hallmarks of HT include diffuse lymphocytic infiltration with or without germinal centers and oxyphilic metaplasia of follicular epithelial cells. We describe a case of a 34-year-old man with HT. Histological examination of the excised thyroid tissue showed diffuse infiltration by numerous plasma cells and a few lymphocytes. To our knowledge there has not been reported HT with these histological findings.